Americans are blessed with a can-do spirit - we don't give up, even in the face of a daunting challenge like a life-threatening illness.
The challenge is sort of capturing the issues that Oregonians feel strongly about and moving forward on those.
I'm getting rid of this idea that you want people to like you. I'm making decisions on what feels right to me. To act in a more carnal way. That's my challenge.
Even as a college professor at Carnegie Mellon and Stanford, I saw myself as an entrepreneur, and I went out, took risks, and tried to invent new things, such as participating in the DARPA Grand Challenge and working on self-driving cars.
Proving yourself in a field where the casualty rate is so notoriously high is an ongoing challenge.
I thought it would be more of a challenge than it was to cater for every size, but as you're aware of a woman's curves - they're kind of like a race track - you can create something glamorous and beautiful.
The challenge of a cathedral is very good for architectural inventiveness.
How many Catholic schools do you think teach the students to question the authority of the Pope? Do you believe Christian schools teach students to question or challenge the authority of Jesus Christ? Do military schools teach the cadets to challenge the authority.
The idea that the law should punish what is rude; that government should protect our tender sensibilities from those who would - quite often with shallow motivations but sometimes with deeper and more serious complaints - challenge our national certainties and rituals, should alarm and anger us.
Women, like men, should try to do the impossible. And when they fail, their failure should be a challenge to others.
I love winning, and I love the challenge.
I like the challenge, week in, week out, of trying to play good, consistent footy.
Playing for Madrid is a great challenge.
The real existential challenge is to live up to your fullest potential, along with living up to your intense sense of responsibility and to be honest to yourself about what you want.
The challenge of directing and interviewing helped me with confidence, and I learnt so much. If I hadn't had the brain hemorrhage, I might never have done it.
I'm extremely willful to win, and I respond to challenges. Scoring titles and stuff like that... it sounds, well, I don't care how it sounds - to me, scoring comes easy. It's not a challenge to me to win the scoring title, because I know I can.
Playing sick. That is so hard to do. It has to be a total mental challenge, as well as the physical challenge.
Do not let anyone tell you it cannot be done. No challenge can match the heart and fight and spirit of America. We will not fail. Our country will thrive and prosper again.
I want to challenge you today to get out of your comfort zone. You have so much incredible potential on the inside. God has put gifts and talents in you that you probably don't know anything about.
How you respond to the challenge in the second half will determine what you become after the game, whether you are a winner or a loser.