Antibiotics are a very serious public health problem for us, and it's getting worse. Resistant microbes outstrip new antibiotics. It's an ongoing problem. It's not like we can fix it, and it's over. We have to fight continued resistance with a continual pipeline of new antibiotics and continue with the perpetual challenge.
Nature is solving all sorts of problems that we throw at her - how to degrade plastic bottles, how to degrade pesticides and herbicides and antibiotics. She creates new enzymes in response to that all the time, in real time.
Building upon the world we created with 'Avatar' has been a rare and incredibly rewarding experience. In writing the new films, I've come to realize that 'Avatar's world, story and characters have become even richer than I anticipated, and it became apparent that two films would not be enough to capture everything I wanted to put on screen.
When the Constitution was written, the founders had no way of anticipating the new technologies that would evolve in the coming centuries.
We haven't lost romance in the digital age, but we may be neglecting it. In doing so, antiquated art forms are taking on new importance. The power of a handwritten letter is greater than ever. It's personal and deliberate and means more than an e-mail or text ever will.
When I was a teenager in New York, I was buying antique clothes. I still am.
Well I think any author or musician is anxious to have legitimate sales of their products, partly so they're rewarded for their success, partly so they can go on and do new things.
More than any other place, New York is where I felt I belonged. I prefer the Lower East Side to any place on the planet. I can be who I am there, and I couldn't do that anywhere I lived as a child. I never fit in when I lived in California, even though that's where my roots are.
That is all that we want, what people want, what people want in New York, in Washington, in Pittsburgh, in any other place in the United States or in Europe. People want to live peacefully. That's what we want.
When I think about 2017, I feel like it was just another year. It was a whirlwind, but I wouldn't have wanted it to play out any other way. I'm glad I was in New York. There's nowhere else I would rather play, and there's no other group of teammates that I would rather be around.
A person who never made a mistake never tried anything new.
I was excited at something new, always liked something new, but give credit to everybody who helped. I didn't do anything alone but try to go to the root of the question and succeeded there.
There was never anything else I wanted to pursue. It was always theater, and movies are a fairly new thing.
The great majority of Baghdad is a slum - a lot of it's new, but it's still slum. It's usually this concrete-block, one-room design with a door and a window, arranged one-up, one-down, often with a shop with nothing in it on the first floor, and then a one-room apartment above it. There's street after street after street of that stuff.
All my life, I never really felt comfortable anywhere in New York, except maybe in an apartment somewhere.
The language of freedom-fighting was so co-opted by the baby boomers in order to express their now-hopelessly compromised ideologies that no other generation could emulate it without a smirk. This has created an apathetic generation in the West, with young people no longer distinguishing between the old order and the new.
I hope that America as a whole, and especially its architects, will become more seriously involved in producing a new architectural culture that would bring the nation to the apex - where it has stood before - and lead the world.
After the 9/11 apocalypse happened in New York City, people, particularly New Yorkers, who breathed in the ash, or saw the results of that, have a tendency to keep seeing echoes and having flashbacks to it.
I think the people who experienced the Apollo missions came away from that experience wondering to themselves, 'When can we get a chance to experience spaceflight?' I've heard that many, many times: that people got into a new career field hoping that they would be able to experience spaceflight.
The New Testament says nothing of Apostles who retired and took it easy.