Many investigators feel uneasy stating in public that the origin of life is a mystery, even though behind closed doors they admit they are baffled.
We will never fully explain the world by appealing to something outside it that must simply be accepted on faith, be it an unexplained God or an unexplained set of mathematical laws.
It is possible that a scientific discovery will be made that humans will later regret because it has awful consequences. The problem is, we probably would not know in advance and, once the discovery is made, it cannot be undiscovered.
The vast majority of terrestrial species are in fact microbes, and scientists have only begun scratching the surface of the microbial realm. It is entirely possible that examples of life as we don't know it have so far been overlooked.
My feeling is that scientific method has the power to account for and interlink all phenomena in the universe, including its origin, using the laws of nature. But that still leaves the laws unexplained.
Astronauts have been stuck in low-Earth orbit, boldly going nowhere. American attempts to kick-start a new phase of lunar exploration have stalled amid the realisation that NASA's budget is too small for the job.