A statistically significant finding gives you a clue, suggesting a promising place to focus your research energy. The significance test is the detective, not the judge. <...> If a result is novel and important, other scientists in other laboratories ought to test and retest the phenomenon and its variants, trying to figure out whether the result was a one-time fluke or whether it truly meets the Fisherian standard of “rarely fails.” That’s what scientists call replication; if an effect can’t be replicated, despite repeated trials, science backs apologetically away. The replication process is supposed to be science’s immune system, swarming over newly introduced objects and killing the ones that don’t belong.