The Omega Point Theory can be a solid foundation of support for all of the great human religions.
Human uploads have such a natural advantage over present-day people in the environment of space, it's exceedingly unlikely flesh-and-blood beings will ever engage in interstellar travel.
A person whose skin is metallic can no more have its reproduction restricted than a black-skinned person. Regarding life as a form of machinery and intelligent machines as people without our environmental limitations is essential in understanding FAP, the Final Anthropic Principle, which deals with evolution in the far future.
What you can show using physics, forces this universe to continue to exist. As long as you're using general relativity and quantum mechanics you are forced to conclude that God exists.